HMOX1 and pregnancy disorder: The results from this study firstly showed the association between the HO-1 (GT)n microsatellite polymorphism in the human HO-1 promoter regulatory region and women with idiopathic recurrent miscarriage in a relatively large Caucasian population, supporting the hypothesis that HO-1 polymorphisms among human population might contribute to some unexplained cases of pregnancy disorders, such as fetal growth retardation and preeclampsia [46].