Figure 4B and Figure 4C show examples of PTEN staining accompanied by miR-205 expression levels in individual cases. Figure 4B demonstrates an undifferentiated carcinoma with high PTEN staining and only a slight up-regulation in miR-205 expression between tumor and adjacent normal tissue (∼1.25 fold). Figure 4C demonstrates a clear cell carcinoma with very low PTEN staining and ∼350 fold up-regulation in miR-205 expression between tumor and adjacent normal tissue. The gene discussed is PTEN; the disease is carcinoma.