The associations involving TGFB1+868 maintained significance in relation to both IHD (OR = 2.14, 95% CI 1.30 to 3.55, P = 0.008) and MI (OR = 2.42, 95% CI 1.30 to 4.50, P = 0.007), whereas the association involving -509 disappeared in these models (adjusted for age and sex). This evidence concerns the gene TGFB1 and myocardial ischemia.