In granuloma-containing biopsies, the proportions of CD11c+ cells co-expressing CD86 was significantly increased (median 88%, range 77-96%), when compared with healthy controls (median 50%, range 4-95) (p = 0.0012), but not significantly different from values in non-granulomatous biopsies from patients (median 82%, range 0-100%). Here, ITGAX is linked to Granuloma.