Reassuringly, the analysis identified CML as possibly associated with major deregulation of these miRNAs and MAPK, ErbB, mammalian target of rapamycin (mTOR) and and vascular endothelial growth factor (VEGF) as the main molecular signaling pathways regulated by these miRNAs. The gene discussed is MTOR; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.