Induction of cytotoxic T cells targeting VEGFR2-positive endothelial cells of the tumor vasculature was achieved by cytosolic delivery of the H-2Db-specific CD8 T-cell epitope VILTNPISM ( = KDR2) from the murine VEGFR2 using Salmonella's T3SS [18]. Here, CD8A is linked to neoplasm.