Although the 2 cases showed intermediate to large sized tumor cells with fine nuclear chromatin, the cases lacked a “starry sky” appearance at low magnification, the tumor nuclei showed marked pleomorphism, and the tumors exhibited immunophenotypes that are not consistent with BL (i.e., BCL2+) or Int. DLBCL/BL (i.e. Ki67<90%) and, therefore, are best classified as DLBCL, NOS. This evidence concerns the gene MKI67 and diffuse large B-cell lymphoma.