Treatment options for HCC (resection), level of GGT (≤ 50 U/L) and AFP (≤ 25 ug/L), tumor number (solitary), vascular invasion (absent), and TNM stage (TNM stage I) were significant factors associated with favorable HCC-specific OS in univariate analysis (Table 3). The gene discussed is AFP; the disease is hepatocellular carcinoma.