In onchocerciasis, the presence of IL-10 is clearly associated with a protective immunological scenario: high IgG4, IL-10 and Treg are associated with low pathology whereas high levels of IgE, IL-4 and eosinophilia are common in patients with severe pathology [9], [22], [64], [67]. This evidence concerns the gene IL10 and Increased total eosinophil count.