Figure 6E demonstrates MRC1 SOMAmer staining performed concurrently with antibody-based immunofluorescence for other targets (cytokeratins and CD31), indicating the feasibility of multiplexing SOMAmer and antibody reagents in histologic studies. Tissue staining with SOMAmers was thus consistent with the homogenate profiles, in which TSP-2 was elevated and MRC1 was decreased in tumor versus healthy tissue. We confirmed the SOMAmer staining patterns of TSP-2 and MRC1 with antibodies Figure 7. The gene discussed is THBS2; the disease is neoplasm.