Disruptions in redox balance and increased oxidative damage are characteristic of many RBC pathologies including hemoglobinopathies such as sickle cell anemia [4] and thalassemia [5], as well as enzyme defects such as glucose-6-phosphate dehydrogenase (G6PD) deficiency [6] and pyruvate kinase (PK) deficiency [7]. This evidence concerns the gene G6PD and hemoglobinopathy.