ORs of associated haplotypes relative to all non-associated ones, denoted as DRB1*X-DQB1*X, showed that four haplotypes increased the risk of MS: *04:05-*03:01 (OR = 2.6, 95% CI 1.8–3.6,P = 8.2×10−8); *13:03-*03:01 (OR = 3.2, 95% CI 1.7–6.0, P = 2.0×10−4); *15:01-*06:02 (OR = 2.2, 95% CI 1.3–3.8, P = 4.0×10−3); and *03:01- *02:01 (OR = 1.8, 95% CI 1.5–2.1, P = 8.7×10−12). The gene discussed is HLA-DRB1; the disease is myeloid sarcoma.