Using a highly conservative correction of P values, TDT analysis confirmed that in Sardinia HLA-related MS susceptibility is associated with *13:03-*03:01 (OR = 2.9), *04:05-*03:01 (OR = 2.4) and *03:01-*02:01 (OR = 2.1) haplotypes, while the previously reported over-transmission of a DRB1*15:01-DQB1*06:02 haplotype was no longer found after correction for multiple comparisons, so the previously reported over-transmission of the DRB1*04:05-DQB1*03:02 haplotype was not confirmed. This evidence concerns the gene HLA-DRB1 and myeloid sarcoma.