T-cells from BE were characterised by a positive staining pattern for IFN-γ in CD4+ (20±9% cells) and CD8+-cells (66±13%) (Figure 6 A+B), which was similar to T-cells from duodenum of BE (CD4+-cells (27±10%) and CD8+-cells (54±11%))(Figure 6 A+B). This evidence concerns the gene CD4 and Barrett esophagus.