This can be observed in the brains of patients with stroke, AD, PD, ALS and other neurodegenerative diseases [7,73-77], and it has been hypothesized that the pathogenesis and progression of neurological diseases is in part due to dysregulation or chronic activation of the NF-κB pathway [6,78,79]. The gene discussed is NFKB1; the disease is neurodegenerative disease.