Not only Cav1, but also the ubiquitously expressed ITSN-1s, a major protein of lung tissue, has been related to lung inflammatory conditions [62], to endosomal disorders associated with the earliest pathogenesis of Alzheimer's disease and Parkinson's diseases [63] as well as cancer [64, 65]. The gene discussed is CAV1; the disease is early-onset autosomal dominant Alzheimer disease.