Particularly, there is concern about the risk for peripheral neuropathy with use of stavudine, especially among patients with lower CD4 cell counts [2] and the risk of rash (including Stevens Johnson syndrome), hypersensitivity, and life-threatening hepatotoxicity with use of nevirapine, especially among women and those with higher CD4 cell counts at initiation of therapy [3–5]. Here, CD4 is linked to Stevens-Johnson syndrome.