Similarly, CD45dimCD34+CD133+ progenitor cell levels were decreased in smokers and TAO patients compared to nonsmokers (44.4±10.6, P = 0.014 and 34.5±4.7, P = 0.002 vs. 76.2±10.2) with the lowest levels measured in TAO patients (Figure 1B). Here, PROM1 is linked to thromboangiitis obliterans.