Macrophage migration inhibitory factor (MIF) is a pleiotropic inflammatory cytokine with chemokine-like functions, which is rapidly released from pre-formed cytoplasmic pools of several cell types (including monocytes/macrophages, B and T cells, endothelial and epithelial cells and cardiomyocytes), in response to various noxious stimuli such as infection, inflammation or hypoxia [15], [16]. The gene discussed is MIF; the disease is infection.