Moreover, MIF levels at admission were increased nearly 30-fold in comparison with healthy volunteers (not having undergone ischemia), but “only" 9-fold in comparison with gender- and age-matched patients admitted to the ICU after cardiac surgery involving cardioplegic arrest and hence (in contrast to the OHCA-patients suffering from total circulatory arrest) “only" myocardial ischemia. This evidence concerns the gene MIF and ischemia.