We identified that transcripts for antimicrobial genes (Pla2g2a, RatNP-3) and extracellular matrix components (Col1a1, Fn1) were induced by AOM treatment in all diets, but to a much lesser extent in bean-fed animals, whereas somatostatin receptor 2 (Sstr2) showed the opposite trend. Here, SSTR2 is linked to infectious otitis media.