Indeed, whereas in nMS patients the percentage of all T- and B-cell subsets analyzed at all time points was not different from that in HD, a lower percentage of recent T emigrants (RTE) and naive B cells as well as a higher percentage of CD8+CD45RA+CCR7− effector memory T (TEMRA) lymphocytes, and of immature and unswitched memory B cells were found in the pmlMS patient before therapy (Table S1). The gene discussed is CCR7; the disease is Huntington disease.