As mentioned in the text above, Hong et al. [3] reported that early-onset susceptibility was attributed to the upregulated gene set called the “predictor gene set” in CRC patients that consists of CYR61, EGR1, FOSB, FOS, VIP, UCHL1, and KRT24. We inspected the associations among the genes listed in Table 1 and the predictor gene set with the text-mining tool, PubGene [4] (www.pubgene.org) (Figure S7). Here, VIP is linked to colorectal carcinoma.