ERVW-1 and coinfection: As shown in Figures 5A and 5C, in the absence of MTb co-infection, replication of mutant viral molecular clones (HIV-1Lai/Bal-env-κB I-Mut (p<0.05), HIV-1Lai/Bal-env-κB II-Mut (p<0.01), and HIV-1Lai/Bal-env-κB I+II-Mut (p<0.01) as well as HIV-1Lai/Bal-env-N5-Mut (p<0.01) were significantly reduced in comparison to the wild-type virus (Figures 5A–5C).