CCL2 and endothelial dysfunction: In this study, we measured peripheral monocyte chemoattractant protein-1 (MCP-1), a proinflammatory chemokine that induces monocyte action leading to cell adhesion and endothelial dysfunction, FFA, and high-molecular weight (HMW) adiponectin, a major adipocytokine that reflects insulin sensitivity, in PIH patients and made repeated measurements of these molecules in women with normal pregnancies throughout the course of pregnancy.