Among several biomarkers, soluble vascular endothelial growth factor (VEGF) receptor 1 (sVEGFR1) (also called soluble fms-like tyrosine kinase 1, sFlt-1) had the strongest association with SOFA score (r = 0.66, p < 0.001) and the highest area under the receiver operator characteristic curve for severe sepsis (0.82) and mortality (0.91) [16]. This evidence concerns the gene VEGFA and Sepsis.