S100A8 and S100A9 proteins became the focus of intensive current research due to their association with numerous human disorders, including acute and chronic inflammatory conditions, autoimmune diseases, cancer, atherosclerosis, cardiomyopathies and neurodegenerative diseases [1–5], as well as due to their crucial roles in normal physiological processes within cells. The gene discussed is S100A9; the disease is autoimmune disease.