There exists known communication between the apoptotic pathway and NFκB through TNF receptor 1-associated protein TRADD [39] and in cancer tumours, NFκB induced upregulation of COX-2 drives the synthesis of prostaglandins that in turn stimulate prostaglandin receptors and activates cell proliferation and angiogenesis [40]. The gene discussed is NFKB1; the disease is neoplasm.