The choice of these parameters was not only guided by the influence of the gonadotrophic hormones (FSH, LH, PMSG, GnRH) on the precocious onset of puberty and the induction of the follicular growth in immature female rats, but also by the clinical usage of these hormones in the treatment of various forms of infertility (ovulatory defects or hypogonadal infertility) [34]. This evidence concerns the gene PLOD1 and Infertility.