AGT and Hypertension: Chronic Ang-(1–7) administration improved LV function of Wistar rats [47] and of diabetic spontaneously hypertensive rats (SHRs) [14] after global ischemia, attenuated the heart failure induced by MI [11], prevented the development of severe hypertension and end-organ damage in SHR treated with L-NAME [13], and reduced the cardiac remodeling in DOCA-salt and in Ang II-infused rats [4, 20].