The mean serum concentration in direct hernia group was 1473.37 ± 118.95 ng/ml with a range of 1244 - 1678 ng/ml while the mean value of serum MMP-2 concentration in indirect hernia group was 1076.07 ± 80.06 ng/ml with values ranging from 967 to 1247 ng/ml, thereby showing a statistically significant difference among groups (Table 1, Fig. 1). The gene discussed is MMP2; the disease is Hernia.