ORMDL3 and childhood onset asthma: In a recent GWA study for asthma, Moffatt et al. genotyped more than 317,000 single-nucleotide polymorphisms (SNPs) in 994 patients with childhood asthma and 1243 people without asthma, and identified that polymorphisms of ORM1-like 3 (ORMDL3) on chromosome 17q21.1 were strongly associated with childhood asthma [39].