Recently, our group (de Carvalho et al.)[24] throughout stable silencing of MAGE-C1/CT7 by shRNA (Short Hairpin RNA) in MM cell lines showed that MAGE-C1/CT7 is involved in survival of malignant plasma cells, protecting myeloma cells against spontaneous as well as drug-induced (bortezomib-inhibitor of the 26S ubiquitin/proteasome) apoptosis. The gene discussed is MAGEC1; the disease is Miyoshi myopathy.