Compared to firstly activated effector T cells, ex vivo generated cytokine-induced killer (CIK) cells have a number of advantages since they exhibit properties different from effector or central memory T cells, that is, CIK cells are activated in an MHC-independent fashion [4, 5], produce proinflammatory cytokines, mainly IFN-γ and IL-4 [6, 7], and exhibit antigen-independent cytolytic activities against a variety of tumour cells. Here, IFNG is linked to neoplasm.