Since multiple ligands and their receptors are involved in neovascularization, including platelet-derived growth factor (PDGF/R), epidermal growth factor (EGFR/R), placenta growth factor (PlGF/R), KIT, fibroblast growth factor (FGF/R), and hepatocyte growth factor (HGF/R), resistance to single antiangiogenic drugs may occur in ovarian cancer patients, blocking such alternative pathways with rational drug combinations that have cross-specificity would be an appropriate molecular targeting strategy [1, 4, 15, 23, 114, 148, 150, 153, 156, 167–170]. Here, EGFR is linked to ovarian cancer.