CYP24A1 and breast carcinoma: For example, CYP24A1 rs27622941 was associated with a more than twofold increased risk of ER- breast cancer among AA women (OR = 2.62, 95% CI = 1.38 to 4.98) and there were no associations in EAs (OR = 0.78, 95% CI = 0.34 to 1.78).