However, with respect to two other psoriasis susceptibility loci (rs1008953/SDC4 and rs2082412/IL12B), risk alleles were enriched in subjects with IL-13-weak patterns (Cliff's delta ≥0.25; P≤0.045; FDR-adjusted P≤0.40) (Figure S14). The gene discussed is IL12B; the disease is psoriasis.