To generate lymphoma cells that express defined foreign antigens, a cell line (291PC, parental cells) was established from a spontaneous λ-hu-MYC lymphoma and transduced with retroviruses encoding either OVA cDNA upstream of IRES-GFP (termed 291OVA) or IRES-GFP as control (termed 291GFP). Here, MYC is linked to lymphoma.