Evidence, recommendations, or both, were found against offering a general physical examination [7], screening for prostate cancer with prostate specific antigen-testing [14], [15], anaemia blood tests [7], coronary heart disease with electrocardiograms or exercise electrocardiograms [7], [16], diabetes with blood glucose [7], [17], [18], kidney disease with serum creatinine [19], urinary dipstick [7], [20], [21], ‘lab tests’ [7], and spirometry [22] for asymptomatic persons. This evidence concerns the gene KLK3 and Familial prostate cancer.