PRRT2 and myocardial infarction: Using different PKC-selective regulators [14], we then demonstrated here that the PKCβII-specific peptide inhibitor, βIIV5-3, prevented the decline in PQC in cultured neonatal cardiac myocytes and that sustained PKCβII inhibition substantially increased survival and cardiac function in myocardial infarction-induced and hypertension-induced heart failure animal models in rats.