These important data extend our previous observation that GAC is correlated with STAT1 [9] and the physiological indication of this finding is significant because elevated STAT1 and type I IFNs levels are not only observed in HAD, but also in many other neurodegenerative diseases [31], [32], [33], [34] though the exact functions of STAT1 and type I IFNs in diseases remains to be elucidated. Here, STAT1 is linked to neurodegenerative disease.