PPARA and colon carcinoma: Members of the peroxisome proliferator-activated receptor (PPAR) family of nuclear receptors (i.e., PPARγ, PPARα, and PPARβ/δ) have been identified as activators of Angptl4 expression in adipose tissue, liver [23], [27], skeletal [28] and cardiac muscle [29], myofibroblasts [30], and colon carcinoma cells [31].