In conclusion, our study demonstrates that MetS+ patients respond with exaggerated triglyceridemia and insulinemia to meals that closely reflect in percent terms the habitual diet in our population and that moderate low-fat/high-CHO and low-CHO/high fat meals are associated with similar changes in serum TG, HDL-C, blood glucose, and plasma insulin in the postprandial period. Here, INS is linked to metabolic syndrome.