Upon a multiple regression analysis, the coexistence of DM and CAD remained significantly associated with increased OC/KDR, BAP/KDR, and OC+BAP/KDR expression ratio versus other patients, independently of age, prevalence of hypertension, concentrations of total cholesterol, HDL and LDL, which were significantly different between the two groups (Delta ± SE 16.7 ± 6.1 for OC/KDR, P = 0.08; 8.7 ± 4.0 for BAP/KDR, P = 0.030; 6.8 ± 2.9 for OC+BAP/KDR, P = 0.023). The gene discussed is KDR; the disease is coronary artery disorder.