In addition, relative unfrequent positivity of Cp DNA in diffuse large B-cell lymphomas respect to OAML, is probably consistent with the possibility that the Cp can lead marginal zone lymphomas to progress to a more aggressive histotype (i.e., diffuse large B-cell lymphomas), which is no longer responsive to (and dependent on) the antigenic stimulation provided by the microorganism [11]. This evidence concerns the gene CP and lymphoma.