In the present study we assessed, in BD patients, standard measures of inflammation (CRP, ESR, leukocyte count), proinflammatory cytokine levels (TNF-α, IL-18), Trolox equivalent antioxidant capacity (TEAC), ferric reducing antioxidant power (FRAP), total antioxidant enzyme activity (AOA), catalase (CAT), superoxide dismutase (SOD) and myeloperoxidase (MPO) activities. This evidence concerns the gene IL18 and Behcet disease.