ESR1 and breast cancer: The molecular subtype of her2/neu over-expressing ductal breast cancers (ER-, PR-, her2/neu+) showed an increased stromal (p = 0.003) and total (p = 0.002) number of FOXP3+ lymphocytes as compared to the other molecular subtypes such as luminal A (ER+, PR+, her2/neu-) or luminal B (ER+, PR+, her/neu2+).