At 48 hours post-infection (gestational day 16), both PMNs (CD11b+, Gr-1+hi, Ly6C+, F4/80−) and macrophages (CD11b+,Gr-1+low, Ly6C+ F4/80+) (Figure S2) were elevated in the bladder of infected pregnant mice compared to sham-treated pregnant mice (Figure 2). Here, ITGAM is linked to infection.