In addition to a strong association especially with HLA DQB1*0602/DRB1*15/DR15 – DQ6 HLA type, narcolepsy has been associated with the presence of TRIB-2 antibodies [17], specific T-cell receptor alpha [11], and purinergic receptor P2RY11 [16] genotypes. This evidence concerns the gene P2RY11 and narcolepsy.