DSG2 and Arrhythmogenic right ventricular dysplasia: The presence of two mutations, i.e., p.Ile70Val in DSG2 and p.Gln133* in PKP2 in the Family I proband, contrasted with unaffected family members who had only one mutation each, suggests that co-segregation of these two mutations in the proband may have led to the development of ARVC.