BIRC5 and non-small cell lung carcinoma: Although we also observed statistically significant effects of survivin expression on survival from studies reported all stages with an HR of 2.13 (95% CI: 1.57–2.89) and from 15 studies reported stage I–III with an HR of 2.07 (95% CI: 1.72–2.48), when we aggregated the studies that reported results for early-stage and advanced-stage NSCLC, the combined HR were 1.97 (95% CI: 0.76–5.14) and 1.93 (95% CI:1.49–2.51) with 3 and 4 studies in each arms, respectively (Figure 1).