In a previous study [30], we proposed that β1,3-galactosyltransferase (β3GalT) may be an important enzyme responsible for regulating the post-translational carbohydrate modification of IgA in tonsillar CD19-positive B cells in patients with IgAN, since a decrease in the expression of the β3GalT gene was significantly correlated with renal dysfunction, the degree of proteinuria, and the severity of the renal injury score. The gene discussed is CD79A; the disease is Abnormal renal physiology.